Original graphical abstract examples

Concrete research stories, clearly visualized.

Explore 30 original research-inspired examples built from specific research objects, methods, measurements, and supported outcomes. Generate an example directly or adapt its evidence-backed structure to your study.

30Complete original examples

4Reusable visual structures

6Research field groups

Original graphical abstract example showing EGF–EGFR–ERK signaling and keratinocyte proliferation. — EGF–EGFR signaling connects to measured keratinocyte proliferation

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Complete graphical abstract examples for different research stories

Filter the original research-inspired examples by field and layout. Each example contains a concrete simulated study and a complete visual narrative; none is presented as a published paper or real experimental record.

30 graphical abstract examples shown

Original Research-inspired Example

BiologyMechanism

EGF–EGFR signaling drives keratinocyte proliferation

Keratinocytes connect membrane EGFR activation with ERK phosphorylation and increased EdU incorporation.

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Original Research-inspired Example

BiologyMechanism

Butyrate strengthens the intestinal organoid barrier

Butyrate-treated organoids show more ZO-1 and lower FITC-dextran permeability than vehicle controls.

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Original Research-inspired Example

BiologyWorkflow

Folate-targeted nanoparticles improve siRNA delivery

Folate decoration increases nanoparticle uptake and lowers target mRNA in receptor-positive tumor cells.

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Original Research-inspired Example

BiologyMechanism

Hypoxia activates HIF-1α–VEGFA expression

Hypoxia stabilizes HIF-1α, promotes VEGFA promoter binding, and raises VEGFA mRNA in endothelial cells.

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Original Research-inspired Example

BiologyWorkflow

Single-cell profiling after influenza vaccination

Matched blood samples and single-cell RNA sequencing reveal an expanded interferon-high monocyte population.

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Original Research-inspired Example

BiologyComparison

MEK inhibition suppresses tumor organoid growth

Treated colorectal tumor organoids show lower phosphorylated ERK and smaller organoid area than controls.

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Original Research-inspired Example

BiologySummary

PD-1 recruits SHP2 and dampens T-cell signaling

Proximity ligation links greater PD-1–SHP2 association with a lower T-cell calcium response.

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Original Research-inspired Example

BiologyComparison

LPS increases macrophage cytokine secretion

LPS-exposed macrophages secrete more TNF-α and IL-6 than vehicle-treated cells after six hours.

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Original Research-inspired Example

ChemistryMechanism

Catalytic cycle of a Suzuki coupling

Oxidative addition, transmetalation, and reductive elimination form biaryl and regenerate Pd(0).

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Original Research-inspired Example

ChemistryComparison

Aqueous ethanol improves Knoevenagel product yield

Matched solvent conditions identify 50% aqueous ethanol as the highest-yield condition for the model reaction.

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Original Research-inspired Example

ChemistryWorkflow

Two-step synthesis and verification of paracetamol

4-Nitrophenol is reduced, acetylated, recrystallized, and verified by infrared spectroscopy and proton NMR.

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Original Research-inspired Example

ChemistryMechanism

Copper electrode converts nitrate to ammonia

Cathodic nitrate reduction proceeds through transient nitrite, with ammonia confirmed after electrolysis.

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Original Research-inspired Example

ChemistryWorkflow

Raman mapping tracks plasma-induced graphene defects

Peak fitting reveals a rising Raman D-to-G ratio as oxygen-plasma treatment duration increases.

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Original Research-inspired Example

Clinical researchWorkflow

Low-sodium counseling reduces ambulatory blood pressure

A randomized twelve-week study compares low-sodium counseling with usual-diet guidance in hypertension.

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Original Research-inspired Example

Clinical researchComparison

HER2 status stratifies trastuzumab response

Pretreatment HER2 groups are compared using the same pathology endpoint after trastuzumab-containing therapy.

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Original Research-inspired Example

Clinical researchWorkflow

Saliva RT-LAMP classification compared with RT-qPCR

Color-based saliva classifications are checked against matched RT-qPCR reference results.

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Original Research-inspired Example

Clinical researchComparison

Exercise improves function in knee osteoarthritis

Exercise and education both reduce pain, while exercise produces greater improvement in chair-rise performance.

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Original Research-inspired Example

Clinical researchSummary

Glucose profiles improve during diet coaching

Repeated monitoring shows higher time in range and lower glucose variability across six months.

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Original Research-inspired Example

Materials scienceWorkflow

Bayesian optimization identifies a stronger aluminum alloy

Computational ranking and tensile validation identify higher yield strength without measurable elongation loss.

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Original Research-inspired Example

Materials scienceMechanism

LiF-rich interphase stabilizes lithium-metal cycling

An artificial interphase makes lithium-ion flux more uniform, reduces dendrites, and raises Coulombic efficiency.

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Original Research-inspired Example

Materials scienceMechanism

Block length shifts micelles from spheres to worms

Longer hydrophobic blocks change amphiphilic polymer assemblies from spherical to worm-like micelles.

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Original Research-inspired Example

Materials scienceComparison

Polydopamine coating reduces steel corrosion

Coated steel develops fewer pits and lower corrosion current than uncoated steel after salt-spray exposure.

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Original Research-inspired Example

Materials scienceSummary

ZnO crystallinity links synthesis temperature to photocatalysis

Higher hydrothermal temperature strengthens wurtzite crystallinity and accelerates ultraviolet dye degradation.

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Original Research-inspired Example

EngineeringWorkflow

Flexible graphene sensor reconstructs finger motion

Finger bending changes sensor resistance; filtering and calibration reconstruct angle with lower error.

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Original Research-inspired Example

EngineeringWorkflow

Biochar and membrane treatment clean dye-containing water

Biochar lowers methylene-blue concentration before membrane filtration further reduces turbidity.

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Original Research-inspired Example

EngineeringMechanism

Force feedback protects soft-fruit robotic grasping

Sensor feedback adjusts gripper torque and reduces peak contact force and slippage versus open-loop control.

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Original Research-inspired Example

EngineeringComparison

Pin-fin cooling lowers temperature with a pressure tradeoff

At matched power and airflow, pin fins cool the chip more but create a larger pressure drop.

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Original Research-inspired Example

Machine learningWorkflow

Retinal image ensemble improves screening sensitivity

A patient-level imaging pipeline compares an ensemble with one network at matched specificity.

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Original Research-inspired Example

Machine learningMechanism

MRI–clinical fusion improves stroke recurrence prediction

Separate MRI and clinical encoders fuse before prediction and outperform either modality alone on held-out data.

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Original Research-inspired Example

Machine learningComparison

Boosted trees trade calibration for sepsis discrimination

On one temporal test set, boosted trees discriminate better while logistic regression calibrates better.

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Read before you reuse

What strong graphical abstract examples have in common

The best graphical abstract examples do not display every result. They establish one reading path, distinguish observations from interpretation, and keep labels legible at the final display size. Use graphical abstract examples to learn visual decisions, never to borrow scientific content.

Learn how to build the structure

One main messageThe reader should identify the supported takeaway within a few seconds.

Visible reading orderArrows, grouping, and whitespace should agree on where the story begins.

Evidence boundariesPredictions, measurements, and hypotheses need visibly different treatment.

Thumbnail legibilityShort labels and controlled contrast preserve meaning when the image is reduced.

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